Why do I need Glyset?
Glyset is one of six types of diabetes pills currently available to treat type 2 diabetes. It helps keep your blood glucose within your target range.
Remember, the cornerstone of diabetes control remains unchanged: it is important to follow a meal plan and to get plenty of physical activity. Diabetes pills are another tool to help you manage your blood glucose.
How does Glyset work?
- Glyset slows the digestion of carbohydrates (sugars and starches) in the small intestine.
- Glyset decreases peaks in blood glucose levels that occur after eating by delaying the absorption of carbohydrates into the bloodstream.
- When used alone, Glyset does not cause low blood glucose (hypoglycemia). If used in combination with some diabetes medications, hypoglycemia may occur.
Guidelines for use
- You should take the prescribed dose of Glyset with the first bite of each main meal.
- You will start with a small dose of Glyset. Your healthcare provider will gradually increase the dose as needed.
- Your healthcare provider may wish to combine Glyset with another type of diabetes pill. When combined with other pills, Glyset may further improve your blood glucose control. Since Glyset works differently than other oral diabetes medications, it will not interfere with their actions.
What should I do if I forget to take my dose of Glyset?
If you forget to take your Glyset, wait until your next scheduled meal and take the usual dose. Write in your record book that you missed a dose. Do not "double" your dose at the next meal.
Can I take Glyset with other medications?
Most medications interact safely with Glyset, however, always remind your healthcare provider what medicines you are taking and when there is a change in your medications. This will help ensure the combinations are safe. Ask if any new medications will affect your diabetes.
What are the side effects of Glyset?
Common side effects include:
- Intestinal gas
- Diarrhea
- Abdominal pain
These symptoms should disappear over time. Call your healthcare provider if you experience severe discomfort or if these side effects last longer than a few weeks.
How do I treat a low blood glucose when taking Glyset?
Glyset alone will not cause low blood glucose (hypoglycemia). Hypoglycemia may occur if you take other oral diabetes medications or insulin along with Glyset. Symptoms of hypoglycemia include being sweaty, shaky, or confused. When hypoglycemia occurs, you need to treat it with one of the following:
- three to four glucose tablets
- 10 ounces of milk
Sucrose (table sugar) is not recommended to treat hypoglycemia because Glyset slows the digestion of this sugar.
Who should not take Glyset?
- People with any type of bowel disease or significant kidney disease should not take this drug.
- The safety of Glyset in pregnant women has not been established. A woman needs to tell her healthcare provider immediately if she becomes pregnant or is planning to become pregnant so that the right medication can be prescribed.
How will I know if Glyset is working?
Check blood glucose levels before and one hour after meals. If your blood glucose and glycohemoglobin A1C are within target range most of the time, the dose is working. If not, review the amount and types of food eaten. Are you taking your medication as prescribed? If your blood glucose remains high, contact your healthcare provider. A change in dose may be needed.
For more information, you may want to purchase our book What You Need to Know About Diabetes - A Short Guide, which can be ordered online. | 
