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Studies for People Without Diabetes

TrialNet Natural History Study for the Prevention of Type 1 Diabetes

Description: The study aims to identify youth and adults at risk for type 1 diabetes by testing for diabetes-related antibodies in relatives of people with type 1 diabetes.  It involves a single blood test.  People who test positive will be eligible for further testing and may be eligible to participate in prevention  trials.

Recruitment: Parents, children, & siblings, ages 1-45, and cousins, grandchildren, nieces, & nephews, ages 1-20, of people with type 1 diabetes.

Contact: If you are interested in learning more about the study, please contact Sarah Szubowicz at (617) 309-4493 or

(CHS #03-33)

Healthy volunteers needed in diabetes study

Description:  Do you want to contribute to cutting edge research in diabetes? The Joslin Diabetes Center in Boston is conducting a new research study to investigate Induced Pluripotent Cells (iPS) in diabetes.  Induced  pluripotent cells (iPS) are cells that are grown forever in a laboratory and can become other types of cells.  These cells may someday help us to predict who is at risk of developing diabetes, which may lead to a better understanding of the disease process or possible new therapies.

Recruiting: If you are between 18-70 years of age and do not have diabetes you may be eligible to participate in the study. Participants will come to the Joslin Diabetes Center in Boston 1-2 times, complete a health history and have a brief physical exam, give a sample of blood, urine and a skin biopsy, have cells grown in a laboratory from their skin sample indefinitely for future use.

Exclusions include: history of bleeding disorders, and history of irregular heart rhythms.

Contact: For more information about this study, please call Julia Ramus at 617-309-4322, or email

(CHS # 08-22)

Sleep effectiveness and glucose and insulin homeostasis

Description: The Beth Israel Deaconess Medical Center (BIDMC) is conducting a research study to see how sleep quality impacts blood sugar control and the body’s handling of energy. The study involves spending 2 nights at the BIDMC Clinical Research Center. There is no testing on the first night. Night 2 includes an overnight sleep study (a test that requires you to wear monitors while you sleep to provide information on your sleep and breathing) and IV catheter placement from which blood samples are taken overnight (to test how the body regulates food intake, storage and energy).

Recruiting:Healthy volunteers and people with pre-diabetes, ages 18-64 years old, who keep a regular sleep schedule, do not take medications for sleep or stimulants, do not have sleep apnea, and are free of tobacco or illegal substances. Pregnant or lactating woman may not participate as there may be hormonal effects on the study findings.

Prediabetes means that you are at risk for developing diabetes based on specific criteria (such as having an elevated blood sugar level or an abnormal response to a sugary drnk-glucose tolerance test performed by your doctor). People with relatives with diabetes might also have increased diabetes risk.

Contact:For additional information about this study, please contact Chris Wood at

(CHS # 2012-P-000187)