Antoine Kaldany, M.D.
Antoine Kaldany, M.D., is the Director of International Programs at Joslin in Boston and Director for Strategy and Program Development at the Joslin Diabetes Center Affiliate in Bahrain. He is a Senior Physician at Joslin Clinic and Associate Clinical Professor of Medicine at Harvard Medical School. He received his medical degree from Faculte Francaise de Medecine, Beirut, Lebanon, and completed his medical training in Internal Medicine, Nephrology and Immunology at the Deaconess Hospital (now Beth Israel Deaconess Medical Center) and the Peter Bent Brigham (now Brigham and Women’s) Hospital. He holds more than 10 U.S. patents and numerous international patents; his issued and pending U.S. patents come under four main categories: biopsy and drug delivery, indwelling catheters, disposable delivery devices for bioengineered drugs and gene therapy, and a peritoneal dialysis access port.
After many years of practice in Internal Medicine, Nephrology and Immunology, Dr. Kaldany shifted his focus to clinical research, particularly telemedicine—remote diagnosis and treatment. In 1979, he used a telex machine in his basement to answer questions from patients overseas, then progressed to fax, e-mail and Internet communications.
In collaboration with a Massachusetts-based company that designs care packages for patients with chronic diseases, Dr. Kaldany is working to implement a “virtual doctor” system that uses the Internet and remote sensing devices to monitor the conditions of patients with diabetes. Patients, who are given blood pressure cuffs, oximeters and wireless sensors, collect data on their weight (once a day), blood glucose levels (four times a day), and blood pressure and blood oxygen (to predict risk of heart attack and stroke). Every night each patient’s data are transmitted to a virtual private network where a clinician immediately analyzes the data. The next morning—via a special television station—the patient receives a personal report and recommendations including referrals for any unusual or dangerous conditions. Such immediate feedback is expected to be a powerful incentive for adherence to diet, exercise and insulin recommendations.
Dr. Kaldany and his team are now enrolling up to 120 patients in a pilot study in Boston to evaluate this remote sensing telemedicine system; a future goal is to use the system internationally. Born in Syria and raised in Lebanon, Dr. Kaldany was instrumental in establishing the Joslin Diabetes Center Affiliate in Bahrain, which is expected to become a central clinical site for Joslin patients throughout the Middle East.
Kaldany A. Autoantibodies to islet cells in diabetes mellitus. Diabetes 28:102-105, 1979.
Kaldany A, Carpenter CB, Suthanthiran M, Garovoy MR, Strom TB, George K. HLA-D activity in lymphocyte subcellular fractions. Transplant Proceed 10:785-788, 1978.