Research Information For Scientists

Critical Literature Analysis 2011: Applying the Data to Clinical Management

Activity Description

Critical Literature Analysis 2011: Applying the Data to Clinical Management

Phoenix, Arizona
Tuesday, January 24, 2012
4:00 PM - 8:45 PM
Statement of Need

Evidence-based medicine integrates the best research evidence with clinical expertise, but how do you determine which studies provide the best evidence? Critical Literature Analysis 2011 will teach you how to evaluate published studies to inform your treatment decisions, address patient concerns driven by media controversy and confusion to strengthen patient adherence, and improve patient care based on the latest scientific research. After a pair of lectures addressing the strengths and weaknesses of various study designs and how to interpret safety surveillance data to determine medication risks vs benefits, you will be able to apply your critical assessment skills in 4 interactive, clinically relevant case-based scenarios based on recent diabetes-related controversies:

  • Should we adjust treatment targets and modalities for older patients with diabetes?
  • Do thiazolidinediones increase the risk of bladder cancer?
  • Do incretin therapies really increase risk of pancreatitis? If so, how do we mitigate it?
  • Do obesity, type 2 diabetes, insulin resistance, and insulin therapy increase the risk of cancer?
Target Audience

This certified live activity has been developed for primary care providers, endocrinologists, diabetologists, and cardiologists. There is no fee to attend this live activity. However, space is limited, and reservations will be accepted on a first-come, first-served basis. Only clinicians can be admitted. Guests who are not clinicians cannot be accommodated.

Topics
4:00 PM Welcome and Opening Remarks
4:15 Study Design: Asking the Question and Understanding the Answer
4:55 Safety Surveillance: Is There a Problem or Not?
5:35 Question-and-Answer Session:
Discussion of the Case Review Process
and Instruction on Review of Initial Cases for the Pretest
6:00 Buffet Dinner Service
6:30 Case Reviews with Table Discussions and Literature Pretest
6:45 Case One
Treating Older People with Diabetes:
Should We Adjust Our Treatment Targets and Modalities?
7:10 Case Two
The Association of a Thiazolidinedione with Bladder Cancer:
Is This a Clinical Concern or Not?
7:35 Case Three
Pancreatitis Risk with Incretin Therapies:
Is It Real, and How Do We Mitigate It?
8:00 Case Four
Type 2 Diabetes and Its Treatments:
Do They Increase the Risk of Cancer?
8:25 Question-and-Answer Session with Panel and Posttest
8:45 Concluding Remarks and Adjournment
Learning Objectives

Participants will be provided with clinically relevant, evidence-based information.
Upon completion of this activity, participants should be able to:

  • Assess the clinical study design, level of evidence, limitations, statistical results, and reported conclusions of clinical trials
  • Summarize the implications of study type on the interpretation of resulting data
  • Discuss the impact of various types of clinical study designs on development of clinical care recommendations for evidence-based practice
  • Apply principles of critical assessment of clinical research trial results to reach accurate conclusions regarding medication/treatment efficacy and safety
  • Use interpretation of recent clinical trial results to choose treatment approaches for patients with diabetes

Faculty

Speakers for this activity will be drawn from the distinguished faculty listed below.*

Aaron M. Cypess, MD, PhD, MMSc
Instructor, Harvard Medical School
Research Associate and Staff Physician
Joslin Diabetes Center
Boston, MA

Kenneth R. Feingold, MD
Professor of Medicine
University of California, San Francisco
Physician and Chief, Endocrine Clinic
San Francisco VA Medical Center
San Francisco, CA

Jason L. Gaglia, MD
Instructor in Pathology
Harvard Medical School
Staff Physician
Joslin Diabetes Center
Boston, MA

Karl Gallegos, MD, MPH
Drug Safety Consultant
Sepracor Inc.
Atlanta, GA

Om P. Ganda, MD
Associate Clinical Professor of Medicine
Harvard Medical School
Director, Lipid Clinic
Joslin Diabetes Center
Boston, MA

Stanley B. Garbus, MD, MPH
President, Garbus Consulting
Co-Founder, Sentrx
West New York, NJ

Osama Hamdy, MD, PhD, FACE
Assistant Professor of Medicine
Harvard Medical School
Medical Director, Obesity Clinical Program
Joslin Diabetes Center
Boston, MA

Robert E. Heinig, MD
Clinical Professor of Medicine
University of Rochester Medical School
Chief of Endocrinology
Rochester General Hospital
Rochester, NY

John L. Leahy, MD
Professor of Medicine
University of Vermont
Burlington, VT

Glenn Matfin, MSc (Oxford), MB ChB, FACE, FACP, FRCP
Harvard Medical School
Senior Physician
Joslin Diabetes Center
Boston, MA

Mark E. Molitch, MD
Professor of Medicine
Division of Endocrinology, Metabolism and Molecular Medicine
Northwestern University Feinberg School of Medicine
Chicago, IL

Medha Munshi, MD
Assistant Professor of Medicine
Harvard Medical School
Director of Joslin Geriatric Diabetes Programs
Beth Israel Deaconess Medical Center
Boston, MA

Jerry P. Palmer, MD
Director, Diabetes Endocrinology Research Center
Professor of Medicine
University of Washington
Director, Division of Endocrinology, Metabolism and Nutrition
VA Puget Sound Health Care System
Seattle, WA

*Faculty list subject to change

Accreditation and Designation of Credit

Joslin Diabetes Center, Boston, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Joslin Diabetes Center designates this live activity for a maximum of 4.0 AMA PRA Category 1 Credits.TM Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This CME live activity was planned and produced in accordance with ACCME Essentials. Health professionals not eligible for continuing medical education credit will receive a certificate of participation that they may submit to their state licensing board for credit.

Disclosure Policy

It is the policy of Joslin Diabetes Center to ensure fair balance, independence, objectivity, and scientific rigor in all activities. All faculty participating in CME activities sponsored by Joslin Diabetes Center are required to present evidence-based data, identify and reference off-label product use, and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.

This activity is supported by educational grants from Amylin-Lilly, and sanofi-aventis U.S. Inc.