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Howard Wolpert, M.D.

Dr. Wolpert is a Senior Physician in the Joslin Clinic Section on Adult Diabetes and the Director of the Insulin Pump Program at Joslin. He has long been involved in the clinical aspects of insulin therapy and is editor of Smart Pumping, published by the American Diabetes Association, and Managing Diabetes with an Insulin Pump: Indications and Interventions, published by Joslin Diabetes Center.

Dr. Wolpert’s research and clinical interests focus on the introduction of new technologies into diabetes care and improving patient adherence to treatment. The introduction of real-time continuous monitors has the potential to revolutionize the management of diabetes. These new devices include a screen, giving patients a continuous graphical readout of their glucose values, and alarms, which sound when the glucose level is either high or low. This additional information can be helpful in optimizing glucose control around exercise and eating, and can also be used to reduce hypoglycemic reactions. 

Dr. Wolpert is involved in randomized controlled trials to evaluate the potential role of real-time continuous glucose monitoring in diabetes management. Some of these studies are directed at the clinical utility of this technology in reversing iatrogenic autonomic failure and hypoglycemic lack of awareness. Effective use of continuous monitoring requires an understanding of a range of issues, including glucose lag times and the factors that alter carbohydrate digestion and absorption rates.

Dr. Wolpert‘s research has been helpful in identifying the educational needs of patients who use continuous monitoring. In related activities Dr. Wolpert is spearheading an initiative to develop training materials to support the adoption of this technology. 

Selected References
Schade DS, Wolpert HA. To pump or not to pump. Diabet Technol Ther 7:845-848, 2005.

Anderson BJ, Wolpert HA. A developmental perspective on the challenges of diabetes education and care during the young adult period. Patient Educ Couns 53:347-352, 2004.

Wolpert HA. A clinician’s perspective on some of the challenges in “closing the loop.” Diabetes Technol Ther 5:843-846, 2003.

Wolpert HA, Faradji RN, Bonner-Weir S, Lipes MA. Metabolic decompensation in pump users due to lispro insulin precipitation. BMJ 324:1253, 2002.

Wolpert HA, Anderson BJ. Young adults with diabetes: need for a new treatment paradigm. Diabetes Care 24:1513-1514, 2001.

Wolpert HA, Anderson BJ. Management of diabetes: are doctors framing the benefits from the wrong perspective? BMJ 323:994-996, 2001.


Page last updated: July 23, 2014