Relieving Stress on Beta Cells May Aid in Diabetes:
BOSTON, Mass. – December 23, 2009 - Cells in your body are constantly churning out poisonous forms of oxygen (oxidants) and mopping them up with a countervailing force of proteins and chemicals (anti-oxidants). This balancing act of oxidative stress is particularly likely to go haywire in beta cells, the insulin-producing cells that malfunction and then start to die off in people with diabetes. Scientists at Joslin Diabetes Center now have found that a relatively little-studied enzyme plays a central role in defending beta cells against oxidants, but is damaged by the high levels of blood glucose produced in diabetes.
Joslin Wins Spot on Discover Magazine’s Top 100 List:
BOSTON – December 8, 2009 – Joslin Diabetes Center researchers have been honored by Discover Magazine in its annual Top 100 list of major scientific accomplishments, for showing that adult humans retain a type of “good” fat previously believed to be present only in babies and children.
In Type 2 Diabetes, Mitochondrial Damage Kills Insulin-Producing Cells:
BOSTON - November 24, 2009 - Over time, patients with type 2 diabetes lose insulin-producing cells, a difficulty that aggravates their disease. Researchers at Joslin Diabetes Center now have identified a mechanism that triggers the problem, giving a chance to find targets for drugs to protect these crucial cells.
Joslin Finds New Drug Targets for Diabetes Eye Complications:
BOSTON – November 1, 2009 – In diabetes patients, high blood glucose levels can end up killing certain cells in the eyes and kidneys, which is why diabetes is the leading cause of adult blindness and of kidney failure. Years ago, scientists identified one main route for this destruction—high glucose produces oxidative stress through the NF-kB molecular pathway—but success has been elusive for drugs targeting that pathway. Researchers at Joslin Diabetes Center now have clarified the complications story by detecting a second, independent pathway, which offers new targets for preventing and treating diabetic eye disease.
Joslin Diabetes Center President and CEO Ranch C. Kimball to Step Down :
BOSTON – May 29, 2009 – Joslin Diabetes Center, the world’s preeminent diabetes research and clinical care organization, announced today that its President and CEO Ranch C. Kimball will step down by the end of August. Kimball has been widely credited with improving the overall health and fiscal stability of the world-renowned organization.
Lloyd Paul Aiello, M.D., Ph.D., of Joslin Diabetes Center Named ARVO 2009 Fellow:
BOSTON – April 29, 2009 – The Association for Research in Vision and Ophthalmology (ARVO) is honored to announce this year’s inaugural class of distinguished Fellows. Lloyd Paul Aiello, M.D., PhD, head of the Joslin Section on Eye Research, was among the group of members recognized for their accomplishments, leadership and contributions to the Association.
Joslin Diabetes Center Opens Affiliate in Dubai :
BOSTON – April 27, 2009 – Expanding its reach in the fight against the global diabetes epidemic, Joslin Diabetes Center today announced the opening of the Joslin Diabetes Center Affiliate at the Dubai Health Authority (DHA).
Shannon Allen Rallies around Team Joslin for Marathon :
BOSTON – April 10, 2009 – It has been almost one year since the Boston Celtics became NBA champions. But, for Shannon Allen, wife of Celtics star guard Ray Allen, it’s also been nearly 12 months since their youngest son, Walker, was diagnosed with type 1 diabetes. For the Allen family, the past months have been filled with ups and downs and certainly some highs and lows.
Joslin Study Pinpoints Role of Insulin on Glucagon Levels:
BOSTON – April 7, 2009 – Researchers at the Joslin Diabetes Center have shown for the first time that insulin plays a key role in suppressing levels of glucagon, a hormone involved in carbohydrate metabolism and regulating blood glucose levels.
Richard R. Crater Joins Joslin Diabetes Center as Chief Financial Officer :
BOSTON – March 19, 2009 – Joslin Diabetes Center today announced Richard R. Crater as chief financial officer. Crater brings to Joslin more than 30 years of experience, including positions as chief financial officer at New York University Medical Center and The Massachusetts General Hospital (MGH).