Researchers restore beta-cell function by deleting old cells

Acceleration of beta-cell aging determines diabetes -- senolysis improves disease outcomes BOSTON – (May 30, 2019) --Research from Joslin Diabetes Center has shown in mice that insulin resistance...
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New Evidence Links Lifespan of Extension to Metabolic Regulation of Immune System

Joslin researchers show that caloric restriction lowers levels of innate immunity and inflammation, leading to increased longevity. Scientists have known for decades that caloric restriction leads to...
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Study identifies enzymes that prevent diabetic kidney disease

DKD protective factors could be used as biomarkers and for personalized clinical intervention BOSTON -- (May 13, 2019) -- A new study from Joslin Diabetes Center has proven that certain biological...
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Pushing early beta-cell proliferation can halt autoimmune attack in type 1 diabetes model

BOSTON -- (May 6, 2019) -- Many in-development cures for type 1 diabetes have understandably focused on tackling the autoimmune aspect of the disease before figuring out a way to replace the destroyed...
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Study sheds light on strategies for managing diabetic macular edema in people with good vision

Initial management with close monitoring appears to provide visual results equal to immediate treatment BOSTON – (April 29, 2019) – Newly available results will influence the standard approach for...
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Breast Milk Analyses Could Lead to New Opportunities for Reducing Earliest Risk of Childhood Obesity

BOSTON – (April 10, 2019) -- New research suggests the composition of breast milk in normal weight mothers differs from that of overweight mothers, and that variations in small molecule metabolites...
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SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

BOSTON - (March 7, 2019) - SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous...
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SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

BOSTON - (March 7, 2019) - SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous...
Read more on SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

Protein Released from Fat Following Exercise Improves Glucose Tolerance, and Health

Another Reason to Exercise! BOSTON – (February 11, 2019) – It’s well-known that exercise improves health, but understanding how it makes you healthier on a molecular level is the question researchers...
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Insulin Signaling Failures in the Brain Linked to Alzheimer’s Disease

BOSTON – (February 11, 2019) -- Scientists continue to find evidence linking Type 2 diabetes with Alzheimer’s disease, the most common form of dementia and the seventh leading cause of death in the...
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In type 1 diabetes, high glucose levels may boost heart damage from autoimmunity

Analysis of clinical results identifies potential biomarkers for increased risk of cardiovascular disease from autoimmune reactions. BOSTON – (November 26, 2018) – Relatively little is known about...
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Using Technology to Manage Type 2 Diabetes Maximizes Time, Resources and Health Outcomes

BOSTON (October 15, 2018) – Harnessing the power of digital health technology --- smart phone apps, telemedicine and mobile health (m-health) --- can provide powerful tools to help people with...
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Nutrients may reduce blood glucose levels

Study in cells and animals shows that one amino acid can provide brief beneficial effects BOSTON – (October 10, 2018) – Type 2 diabetes is driven by many metabolic pathways, with some pathways driven...
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