Metabolic Pathways of Increased Cardiovascular Risk in Type 2 Diabetes


​The purpose of this study is to examine the mechanisms through genetic factors that may predispose people with diabetes to cardiovascular (heart) disease. Understanding how these genes work may help scientists find new ways to prevent cardiovascular diseases in people with diabetes for the future.

​The study involves:

  • One visit to the Joslin Diabetes Center, during which participants will undergo blood tests (fasting blood glucose, kidney function tests, cholesterol), urine tests, and an ECG.

  • A CT scan to measure the amount of calcium in the coronary arteries. This will be performed at the Brigham and Women's hospital right after the visit at the Joslin or on another day up to three months after the study visit.

  • All study-related procedures and tests are at no charge.

  • All information will be held strictly confidential.

Monetary compensation and parking validation will be provided for eligible study participants.


This study is no longer recruiting.


Kyla Murray or Caroline Bulcao Souza at 866-622-3885 or joslinheartstudy [at] (by email)target="_blank" title="Email us".