Fatty liver in type 1 diabetes


The purpose of this study is to examine the existence of nonalcoholic fatty liver disease (NAFLD) in people with type 1 diabetes and factors associated with it. NAFLD refers to fat deposits in the liver with no or minimal alcohol intake, and is very common in type 2 diabetes, however, information are very limited in people with type 1 diabetes. NAFLD may increase the risk of heart disease and, in some cases, can manifest as liver inflammation (nonalcoholic steatohepatitis or NASH) which can lead to scarring (fibrosis). Understanding how NAFLD presents in people with type 1 diabetes may help scientists find new ways to prevent NASH fibrosis and heart disease in the future.

The study involves:

  • One study visit for about 1 hr to Joslin Diabetes Center
  • A blood sample around 30 ml (two tablespoons)
  • FibroScan, to measure fat and stiffness of the liver. This is a 5-7 minutes test similar to ultrasound
  • parking validation, in addition to monetary compensation
  • All study-related tests are at no charge


You may be eligible if you are between the ages of 18 and 75 and have been diagnosed with type 1 diabetes.


If you have interest in finding out more about participating in this study please call the study coordinator: Shilton Dhaver at (617) 309-4152 or send an email to Shilton.dhaver [at] joslin.harvard.edu