Type 1

PERL Study

PERL Study

A Multi-Center Clinical Trial of Allopurinol to Prevent Renal Function (GFR) Loss in Type 1 Diabetes Description: ​The purpose of this study is to find out whether a medication called allopurinol can...
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PERL Study

Type 1

PERL-Fenofibrate Study

PERL-Fenofibrate Study

A Pilot Study of Fenofibrate to Prevent Kidney Function Loss in Type 1 Diabetes Description: The purpose of this study is to learn more about the effect of a drug called fenofibrate on kidney function...
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PERL-Fenofibrate Study

Type 2

PIONEER 8 Trial

Glucose Control

PIONEER 8 Trial

Efficacy and Safety of Oral Semaglutide versus Placebo in Subjects with Type 2 Diabetes Mellitus Treated with Insulin Description: ​The purpose of this trial is to study the effects of an...
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PIONEER 8 Trial

PROMISE: PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life

Are You an Expectant Parent with Type 1 Diabetes? Eligibility Baby’s mother or father has type 1 diabetes for at least 12 months, or a full sibling of the baby has type 1 diabetes Mother 8-24 weeks...
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PROMISE: PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life

Type 1
Pediatric Clinical Research

SENCE Study

Glucose Control

SENCE Study

Strategies to Enhance New CGM use in Early Childhood (SENCE) Description: ​A clinical trial to find out how well the continuous glucose monitor works in children less than 8 years old with T1D and...
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SENCE Study

Type 1

T-Rex Study

T-Rex Study

Exploratory Study of CLBS03 in Children with Recent Onset T1D Description: ​This study aims to assess if one's own expanded regulatory T cells can rebalance the immune system, decreasing the attack on...
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T-Rex Study

Type 1
Pediatric Clinical Research

T1D Exchange

T1D Exchange

The T1D Exchange Type 1 Diabetes Network-Pediatric, Adolescent, and Young Adult Section Description: ​The Type 1 Diabetes (T1D) Exchange is a nationwide registry collecting information about children...
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T1D Exchange

Type 1

T1GER Study

T1GER Study

SIMPONI® to Arrest Beta-Cell Loss in Type 1 Diabetes Description: ​This study aims to determine if the drug SIMPONI® (golimumab) can preserve beta-cell function in children and young adults with newly...
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T1GER Study

Type 1
Type 2

The CIAO Study

The CIAO Study

Insulin dosing practices in persons with diabetes on multiple daily injections Description: ​This study uses an electronic dose-recording device to examine dosing in individuals on multiple daily...
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The CIAO Study

Type 2

The IGNITE Study

Technology

The IGNITE Study

Promoting Lifestyle Changes with Mobile Health Technologies for Overweight or Obese Older Adults with Type 2 diabetes – Feasibility & Acceptability Study Description: ​This study examines the effect...
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The IGNITE Study

Type 1

The TANGO Study

Technology

The TANGO Study

Technological Advances in Glucose Management in Older Adults Description: ​This study assesses a new technology that aids the communication of health information amongst patients, family members...
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The TANGO Study

Type 2
Pediatric Clinical Research

TODAY - 2

TODAY - 2

Treatment Options for Type 2 Diabetes in Adolescents and Youth 2 Phase 2 Description: ​The purpose of TODAY 2 Phase 2 is to find out if the drug treatment or lifestyle program participants received...
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TODAY - 2

Type 1
People without diabetes
Pediatric Clinical Research

TrialNet

TrialNet

TrialNet Natural History Study for the Prevention of Type 1 Diabetes Description: ​The study aims to identify youth and adults at risk for type 1 diabetes by testing for diabetes-related antibodies in...
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TrialNet