close up of lab testing

Supporting Medical Discoveries

Joslin's Diabetes Research Center (DRC) is a world-class research institution that has been funded by the National Institutes of Health (NIH/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for more than 30 years.

Our researchers are at the forefront of discoveries that help clinicians better understand diabetes and how to treat their patients. Through a combination of basic research and clinical research, we're unlocking a new understanding of what causes diabetes, and how patients can avoid complications - or getting the disease altogether. 

To support major research programs and their productivity, our core laboratories offer services, reagents, specialized technical expertise, and education. Explore Joslin's cores and learn how you can work with us on your research program.

Explore Our DRC Cores

When it comes to diabetes, Joslin is a research powerhouse. Our cores provide critical services to keep our research initiatives moving forward.

Animal Physiology

The purpose of the Animal Physiology Core is to provide technically advanced physiological evaluation of metabolism in diabetes, obesity, and the associated complications in rodents for Joslin Diabetes Research Center investigators and outside users.

Clinical Translational Research Core

The Joslin Clinical Translational Research Center offers a safe, comfortable, and effective environment to conduct outpatient clinical research studies.

Enrichment Core

The Joslin Enrichment Core facilitates the exchange of research information and discussions among investigators, fellows, and students within the Joslin Diabetes Center, as well as between Joslin staff and outside researchers with similar interests.

Flow Cytometry

The Joslin Flow Cytometry Core provides reliable and affordable cell sorting and flow cytometry services to its users so that they can isolate, analyze, and study cells that increase our understanding of diabetes and its complications, and ultimately, develop treatments and cures for these diseases.

Genome Editing Core

The Genome Editing Core (GEC) provides investigators with resources to manipulate the genome of human cell lines and laboratory mice with the aim of studying the genetics underlying diabetes and its complications.

Molecular Phenotyping & Genotyping

The objective of the Molecular Phenotyping and Genotyping Core is to support Joslin and external investigators in the study of molecular mechanisms of disease by providing equipment, expertise, and services in molecular phenotyping.

Explore Other Joslin Cores

Advanced Microscopy Core

Tissue morphology and knowledge of the localization of specific proteins within a cell are integral to understanding cellular metabolism, the causes and consequences of diabetes, and new advances for the treatment of diabetes.

Bioinformatics & Biostatistics

The Bioinformatics and Biostatistics Core at Joslin Diabetes Center offers support for data-driven projects related to basic, clinical, and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of bioinformatics and biostatistics.

Islet Isolation Core

​​​​The objective of the Islet Isolation Core is to provide isolated Islets of Langerhans from rats and mice for investigators. Thanks to years of experience, the Core can predictably provide islets that are high in quantity, quality and purity.

Executive Committee

Keith Blackwell
Keith Blackwell, MD, PhD
Section Head, Islet Cell and Regenerative Biology
Acting Section Head, Immunobiology
Senior Investigator
Professor of Genetics, Harvard Medical School
Susan Bonner-Weir
Susan Bonner-Weir, PhD
Senior Investigator
Professor of Medicine, Harvard Medical School
goodyear
Laurie Goodyear, PhD, MS
Senior Investigator
Professor of Medicine, Harvard Medical School
Carl Ronald Kahn
Ronald Kahn, MD
Chief Academic Officer
Section Head, Integrative Physiology and Metabolism
Senior Investigator
Mary K. Iacocca Professor of Medicine, Harvard Medical School
George King
George King, MD
Chief Scientific Officer
Section Head, Vascular Cell Biology
Founder/Director, Asian American Diabetes Initiative
Professor of Medicine and Ophthalmology, Harvard Medical School
Lori Laffel
Lori Laffel, MD, MPH
Chief, Pediatric, Adolescent, and Young Adult Section
Section Head, Clinical, Behavioral and Outcomes Research
Senior Investigator
Professor of Pediatrics, Harvard Medical School
shoelson
Steve Shoelson, MD, PhD
Associate Research Director
Section Head, Pathophysiology and Molecular Pharmacology
Senior Investigator
Helen and Morton Adler Chair in Structural Biology
Professor of Medicine, Harvard Medical School
Acting Section Head, Immunobiology

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