close up of lab testing

The Joslin DRC

Since its founding in 1898, the mission of the Joslin Diabetes Center has been to improve the lives of patients with diabetes through research, clinical care, and education to find new treatments, improve care and prevent disease in those at risk. Over the past 30 years, this research at Joslin has been supported by NIH/NIDDK through a Diabetes Research Center (DRC) Program Grant led by George L. King, MD.

The aims of this program are to:

  1. Create an environment that supports world-class investigation in diabetes and metabolism.
  2. Sustain and strengthen the diabetes research infrastructure through core laboratories that provide outstanding expertise and cutting edge technologies.
  3. Catalyze new diabetes research and multidisciplinary collaborations that transform the field of diabetes research through support of early stage research (Pilot and Feasibility Program) and a comprehensive program of seminars and symposia (Enrichment Program).
  4. Translate new knowledge to improved care and prevention.

Explore Our DRC Cores

When it comes to diabetes, Joslin is a research powerhouse. Our NIH/NIDDK funded cores provide critical services to keep our research initiatives moving forward.

Animal Physiology

The purpose of the Animal Physiology Core is to provide technically advanced physiological evaluation of metabolism in diabetes, obesity, and the associated complications in rodents for Joslin Diabetes Research Center investigators and outside users.

Clinical Translational Research Core

The Joslin Clinical Translational Research Center offers a safe, comfortable, and effective environment to conduct outpatient clinical research studies.

Flow Cytometry

The Joslin Flow Cytometry Core provides reliable and affordable cell sorting and flow cytometry services to its users so that they can isolate, analyze, and study cells that increase our understanding of diabetes and its complications, and ultimately, develop treatments and cures for these diseases.

Genome Editing Core

The Genome Editing Core (GEC) provides investigators with resources to manipulate the genome of human cell lines and laboratory mice with the aim of studying the genetics underlying diabetes and its complications.

Molecular Phenotyping & Genotyping

The objective of the Molecular Phenotyping and Genotyping Core is to support Joslin and external investigators in the study of molecular mechanisms of disease by providing equipment, expertise, and services in molecular phenotyping.

Explore Joslin Funded Cores

Advanced Microscopy Core

Tissue morphology and knowledge of the localization of specific proteins within a cell are integral to understanding cellular metabolism, the causes and consequences of diabetes, and new advances for the treatment of diabetes.

Bioinformatics & Biostatistics

The Bioinformatics and Biostatistics Core at Joslin Diabetes Center offers support for data-driven projects related to basic, clinical, and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of bioinformatics and biostatistics.

Islet Isolation Core

​​​​The objective of the Islet Isolation Core is to provide isolated Islets of Langerhans from rats and mice for investigators. Thanks to years of experience, the Core can predictably provide islets that are high in quantity, quality and purity.

Executive Committee

George King
George King, MD
Chief Scientific Officer
Section Head, Vascular Cell Biology
Founder/Director, Asian American Diabetes Initiative
Professor of Medicine and Ophthalmology, Harvard Medical School
Keith Blackwell
Keith Blackwell, MD, PhD
Section Head, Islet Cell and Regenerative Biology
Acting Section Head, Immunobiology
Senior Investigator
Professor of Genetics, Harvard Medical School
Susan Bonner-Weir
Susan Bonner-Weir, PhD
Senior Investigator
Professor of Medicine, Harvard Medical School
Laurie Goodyear, PhD, MS
Senior Investigator
Professor of Medicine, Harvard Medical School
Carl Ronald Kahn
Ronald Kahn, MD
Chief Academic Officer
Section Head, Integrative Physiology and Metabolism
Senior Investigator
Mary K. Iacocca Professor of Medicine, Harvard Medical School
Lori Laffel
Lori Laffel, MD, MPH
Chief, Pediatric, Adolescent, and Young Adult Section
Section Head, Clinical, Behavioral and Outcomes Research
Senior Investigator
Professor of Pediatrics, Harvard Medical School
Steve Shoelson, MD, PhD
Associate Research Director
Section Head, Pathophysiology and Molecular Pharmacology
Senior Investigator
Helen and Morton Adler Chair in Structural Biology
Professor of Medicine, Harvard Medical School
Acting Section Head, Immunobiology

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