How We're Advancing Care
The section on Clinical, Behavioral, and Outcomes Research aims to elucidate the underlying genetic and environmental determinants of type 1 and type 2 diabetes and its complications, and develop new treatments to prevent or delay the development of diabetes and its complications in high-risk individuals.
The section has an active clinical research environment to train future investigators. The scope of ongoing investigations ranges from small physiologic projects to NIH-funded multi-center trials. There are over 300 unique, active IRB-approved human protocols at the Joslin, of which about 175 involve active patient participation.
These studies include a wide range of investigations that can be described as observational (55 percent) or interventional (45 percent); single site (60 percent) or multicenter (40 percent); and involve participants who are adult (80 percent), pediatric (7.5 percent), or both (10 percent). Studies are led by more than 47 PIs (many of whom are in other Joslin sections). Investigators in the section collaborate extensively with members of basic research sections at the Joslin and with investigators in the surrounding Harvard-affiliated teaching hospitals and at other academic institutions.